@ilyeser I'm in a similar boat. Here's my current status with Reshade + Cyberpunk + Proton + Nvidia. My launch command is very similar to yours. I tried it both via gamescope and without, the results are the same either way.
Nvidia driver 595.45.04
proton-cachyos-slr 1:10.0.20260320-1 (based on proton experimental-10.0-20260312)
Reshade 6.7.3.2148
Reshade uninstalled: Game runs 100% stable in HDR with either PROTON_VKD3D_HEAP=0 or 1 (I don't know if it makes any difference currently, performance seems about the same)
Reshade installed:
With PROTON_VKD3D_HEAP=1 main menu loads, game loads and runs, but graphics are scrambled. Interestingly, the inventory screen renders the 3d character model just fine:
(Both screenshots with Reshade enabled.)
With PROTON_VKD3D_HEAP=0 it hangs every time at the "Welcome to Night City" loading screen just before the main menu. Logs from both modes above attached:
There was one combination of Nvidia 590 drivers and an older proton / Reshade build where I could get it playable and looking correct with Reshade for anywhere between 30 seconds and a couple minutes before it would crash or hang, which wasn't particularly useful. It sounds like that's where you were at back when you posted this. But anything more recent consistently hangs or crashes at the loading screen.
I'm hopeful that when the Nvidia VKD3D heap support gets fully implemented this will get fixed.
proton experimentalx1 2026-03PROTON_VKD3D_HEAP=0x1 2026-03PROTON_VKD3D_HEAP=1x1 2026-03DXVK_HDR=1x1 2026-01DXVK_NVAPI_DRS_NGX_DLSS_SR_OVERRIDE_RENDER_PRESET_SELECTION=RENDER_PRESET_Kx1 2026-01PROTON_ENABLE_HDR=1x1 2026-01PROTON_ENABLE_WAYLAND=1x1 2026-01PROTON_LOG=1x1 2026-01WINEDLLOVERRIDES="d3dcompiler_47=n;dxgi=n,b"x1 2026-01
The game just crashes (sometimes at start, sometimes randomly while playing) when both DLSS and Reshade Addon are enabled. Even after the recent patch of Reshade Addon (v6.7).
Software information
Cyberpunk 2077 (crashes randomly while playing, sometime at start)
The Witcher 3
System information
Log files
proton-logs.tar.gz