Leaving comment also here.
It seems that I have same issue on RX 580 with ACO.
Works with previous Proton 4.2-9.
Strangely it worked OK in Blood Aquaducts, and in Act 4 town, but in Act 3 town it doesn't load.
Crash trigger entry is the same in my log file.
Hello @phush0, your issue report over at https://github.com/daniel-schuermann/mesa/issues/93 is the better place to track this issue.
As a side note, we're using one issue report per unofficially supported game title, so feel free to add a note to #58 if your issue turns out to be outside of the driver.
proton 4.2-9x1 2019-07
Compatibility Report
System Information
I confirm: