This looks like a line of interest from the log: err:module:import_dll Library PhysXLoader.dll (which is needed by L"Z:\\home\\bausch\\.local\\share\\Steam\\steamapps\\common\\Cryostasis\\Cryostasis.exe") not found
Installing physx does not helped, physx+win32 prefix too. Works when installed from lutris.
Retesting with proton 5.0-2.
Vanilla proton:
steam-7850.log
Protonfixes with physx:
steam-7850.log
Protonfixes with physx+win32 prefix:
steam-7850.log
Works now with latest proton + physx.
Wine bug is fixed now, only dxvk bug is remains.
proton 5.0-2x1 2020-02physxloader.dllx1 2020-01
Compatibility Report
System Information
I confirm:
steam-7850.log
Symptoms
Game does not start.
Reproduction