Hello @l4dbill8745, we're using one issue report per unofficially supported game title, so I've gone ahead and transferred this issue report to https://github.com/ValveSoftware/Proton/issues/1308#issuecomment-997131445.
proton 6.3-8x1 2021-12PROTON_USE_WINED3Dx1 2021-12
I have been able to get Arma 2 working with a solution found in Arma 2 (33900). However I have encountered another issue with the game being completely red shifted.
I am not sure if proton is the source of this issue but I am making issue reports on the softwares that I think could be responsible.
I am using Proton 6.3-8, on Manjaro 21.2c. I have not had this issue with any other games and I have not done anything to my knowledge that could be causing this.
Edit with addition possibly helpful information
Additionally, I have been running every game I play, with proton, with the PROTON_USE_WINED3D option because if I do not use this option the games crash instantly. I use this setting for every game and have not seen a similar effect in any.