Compatibility Report

• Name of the game with compatibility issues: The Binding of Isaac: Rebirth (Afterbirth+ DLC)
• Steam AppID of the game: 570660 (AppID of parent game, The Binding of Isaac: Rebirth (250900))

System Information

• GPU: AMD Custom GPU 0405 (vangogh, DRM 3.45)
• Driver/LLVM version: 4.6 (Compatibility Profile) Mesa 22.0.0-devel (git-676ccacebc), LLVM 13.0.0
• Kernel version: 5.13.0-valve10.1-1-neptune-02144-g7fffaf925dfb
• Link to full system information report as Gist: https://gist.github.com/GunstarXX/90d46e15c8fe88d27b31e46731755630
• Proton version: 7.0-2

I confirm:

• [X] that I haven't found an existing compatibility report for this game.
• [X] that I have checked whether there are updates for my system available.

Symptoms

As long as the Afterbirth+ DLC is installed, the game will crash instantly and kick me back to Steam.

Reproduction

Download all DLC for Binding of Isaac Rebirth up to Afterbirth+ on your Steam Deck and attempt to launch the game.