App ID: 35000
Proton Versions tested: GE-Proton-8-27, Proton Experimental, Proton 8.0-5, Proton 7.0-6
You will not hear any audio in game audio if you using pipewire. The only sound you will hear is the cutscenes, but during gameplay you will not hear anything.

Server Name: PulseAudio (on PipeWire 1.0.1)
Server Version: 15.0.0
Default Sample Specification: float32le 2ch 48000Hz

I have a feeling this could possibly be fixed or made to work without OpenAL if I changed my backend to regular pulseaudio or if I tinkered in qpwgraph but noone uses pulseaudio and not many people have tried qpwgraph including myself. The solution I provided streamlines the user experience for the avg joe.

Side note: adding and then removing env SDL_AUDIODRIVER=pipewire gamemoderun %command% to launch options made the audio stop working again (only working in cutscenes) I had to reinstall the game and openal again.