The dxvk-1.6 setup_dxvk.sh script didn't work for me. The issue was that winepath appended \r at the end of the path, so the dstfile variable in installFile would be garbage and the script would complain with "File not found".

I fixed this by removing the \r suffix from win64_sys_path and win32_sys_path as follows:

win64_sys_path=$($wine64 winepath -u 'C:\windows\system32' 2> /dev/null)
win64_sys_path="${win64_sys_path/$'\r'/}"
if $wow64; then
  win32_sys_path=$($wine winepath -u 'C:\windows\system32' 2> /dev/null)
  win32_sys_path="${win32_sys_path/$'\r'/}"
fi