Almost certainly running out of address space (see #1318).
Try setting d3d9.evictManagedOnUnlock = True in your DXVK config (more about that in the README)
I put the suggested config, and at the moment the problem of crash has disappeared, but now when the character walk or run, i can see as if the camera jump, as if had short frame cuts...
You'll have to pick between either of those. It's not something that can be fixed unfortunately.
why close the issue? please leave open or reopen it, for author's knowlegment and possible fix.
Nothing extracted yet.
I played borderlands 2 a few months with other version of dxvk, and works fine, but with latest versions of dxvk, the game stop responding ramdomly, i can play 1 hour or play 5 minutes, and the game simply crash without error message. I played without dxvk and the problem is gone.
I don´t know if this problem occurs in borderlands the pre-sequel. Maybe yes.