running with DXVK v1.7.3L-03f11ba does not show this issue, so it's new in DXVK v1.8.1

dmesg reports:

[ 1095.946288] WARNING: CPU: 9 PID: 5289 at drivers/gpu/drm/amd/amdgpu/amdgpu_ttm.c:762 amdgpu_ttm_tt_get_user_pages+0x2a6/0x310 [amdgpu]
[ 1095.946438] Modules linked in: uinput rfcomm xt_CHECKSUM xt_MASQUERADE xt_conntrack ipt_REJECT nf_reject_ipv4 nft_compat nft_counter nft_chain_nat nf_nat nf_conntrack nf_defrag_ipv6 nf_defrag_ipv4 nf_tables nfnetlink tun bridge stp llc snd_hda_codec_realtek snd_hda_codec_generic snd_hda_codec_hdmi ledtrig_audio snd_hda_intel snd_intel_dspcfg intel_rapl_msr soundwire_intel intel_rapl_common soundwire_generic_allocation cmac snd_soc_core bnep snd_compress snd_pcm_dmaengine soundwire_cadence x86_pkg_temp_thermal snd_hda_codec intel_powerclamp snd_hda_core coretemp sunrpc ac97_bus snd_hwdep kvm_intel btusb snd_seq btrtl snd_seq_device btbcm vfat btintel fat snd_pcm kvm iTCO_wdt intel_pmc_bxt eeepc_wmi bluetooth iTCO_vendor_support irqbypass snd_timer asus_wmi mei_me rapl intel_cstate sparse_keymap snd i2c_i801 ecdh_generic rfkill intel_uncore video wmi_bmof intel_wmi_thunderbolt pcspkr ecc joydev soundcore mxm_wmi lpc_ich i2c_smbus mei binfmt_misc zram ip_tables amdgpu drm_ttm_helper ttm
[ 1095.946495] iommu_v2 gpu_sched i2c_algo_bit drm_kms_helper cec crct10dif_pclmul crc32_pclmul drm crc32c_intel ghash_clmulni_intel nvme e1000e nvme_core wmi fuse
[ 1095.946506] CPU: 9 PID: 5289 Comm: Cyberpunk2077.e Tainted: G W 5.11.11-200.fc33.x86_64 #1
[ 1095.946508] Hardware name: ASUS All Series/X99-A, BIOS 4101 07/10/2019
[ 1095.946509] RIP: 0010:amdgpu_ttm_tt_get_user_pages+0x2a6/0x310 [amdgpu]
[ 1095.946614] Code: fb 48 89 ef e8 eb 4d ac fb e9 44 ff ff ff 48 c7 c6 d1 aa a5 c0 bf 02 00 00 00 41 be f2 ff ff ff e8 6f f5 f1 ff e9 28 ff ff ff <0f> 0b 41 be f2 ff ff ff e9 1b ff ff ff 41 be fd ff ff ff e9 10 ff
[ 1095.946617] RSP: 0018:ffff9827c1f3fba8 EFLAGS: 00010282
[ 1095.946619] RAX: ffff8981da6beb00 RBX: ffff89813053d8a0 RCX: 0000000000000001
[ 1095.946620] RDX: 0000000000000dc0 RSI: ffff8981da6beb00 RDI: ffff898084da5400
[ 1095.946622] RBP: ffff898081838440 R08: 0000000000000100 R09: ffff8981da6beb00
[ 1095.946623] R10: 0000000000000000 R11: 0000000000000000 R12: ffff9827c1f3fc50
[ 1095.946624] R13: 0000000000000001 R14: ffff898084da5458 R15: ffff898084da5400
[ 1095.946626] FS: 000000002eb93640(0000) GS:ffff89879fc40000(0000) knlGS:000000013ff90000
[ 1095.946628] CS: 0010 DS: 0000 ES: 0000 CR0: 0000000080050033
[ 1095.946629] CR2: 00000000261b5000 CR3: 000000021802a001 CR4: 00000000001706e0
[ 1095.946631] Call Trace:
[ 1095.946635] amdgpu_cs_ioctl+0x6e1/0x1ce0 [amdgpu]
[ 1095.946741] ? __wake_up_common+0x80/0x180
[ 1095.946746] ? amdgpu_cs_find_mapping+0xe0/0xe0 [amdgpu]
[ 1095.946855] drm_ioctl_kernel+0x86/0xd0 [drm]
[ 1095.946890] drm_ioctl+0x20f/0x3a0 [drm]
[ 1095.946908] ? amdgpu_cs_find_mapping+0xe0/0xe0 [amdgpu]
[ 1095.947010] ? selinux_file_ioctl+0x122/0x1c0
[ 1095.947014] amdgpu_drm_ioctl+0x49/0x80 [amdgpu]
[ 1095.947099] __x64_sys_ioctl+0x83/0xb0
[ 1095.947102] do_syscall_64+0x33/0x40
[ 1095.947106] entry_SYSCALL_64_after_hwframe+0x44/0xa9
[ 1095.947109] RIP: 0033:0x7fa745fd95db
[ 1095.947111] Code: 89 d8 49 8d 3c 1c 48 f7 d8 49 39 c4 72 b5 e8 1c ff ff ff 85 c0 78 ba 4c 89 e0 5b 5d 41 5c c3 f3 0f 1e fa b8 10 00 00 00 0f 05 <48> 3d 01 f0 ff ff 73 01 c3 48 8b 0d 6d b8 0c 00 f7 d8 64 89 01 48
[ 1095.947112] RSP: 002b:000000002eb8e6c8 EFLAGS: 00000246 ORIG_RAX: 0000000000000010
[ 1095.947113] RAX: ffffffffffffffda RBX: 000000002eb8e740 RCX: 00007fa745fd95db
[ 1095.947114] RDX: 000000002eb8e740 RSI: 00000000c0186444 RDI: 0000000000000093
[ 1095.947115] RBP: 00000000c0186444 R08: 00007fa720f8b0f0 R09: 000000002eb8e710
[ 1095.947116] R10: 0000000000000000 R11: 0000000000000246 R12: 00007fa720311cd0
[ 1095.947117] R13: 0000000000000093 R14: 000000007e0f7480 R15: 00007fa720f8b0a0
[ 1095.947118] ---[ end trace 8665455d224ebb76 ]---
[ 1095.947120] [drm:amdgpu_cs_ioctl [amdgpu]] ERROR Failed to process the buffer list -14!

Cyberpunk2077_dxgi.log