dxgi is mostly irrelevant in regards to rendering performance unless, as an example, the game takes a different path depending on the GPU vendor it sees through it.
DXGI is used to configure the monitor or interact with the Windows window system.
It's used by both D3D11 and D3D12.
The actual rendering work happens in either of those two APIs. The Dead Space Remake uses D3D12, which DXVK doesn't support. You'd need vkd3d-Proton for that.
That said, if there was some magic way to improve performance in the game, the developers of vkd3d-Proton would've already done it. You can't magically fix Dead Spaces performance problems with a D3D implementation because that D3D implementation only gets low level commands from the game and has no way of knowing what each of those commands is for. So it has to precisely execute what the game tells it to. To fix performance issues in that game, you'd need the source code of the game and make changes there.
Nothing extracted yet.
Could you improve performance in Dead space remake with dxgi ?